When I first became aware of the concept of defense in depth, the extent of depth was servers and workstations. At that time, most people felt that it was cost ineffective to protect both layers. I remember some very big, established names making very public statements of how we didn't need anti-virus software on servers, as it only added overhead, and offered little protection since a majority of viruses are boot sector infectors. These people were industry insiders and very respected "experts" at the time.
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